What is Strattera? Reviews of parents and specialists about this drug will be presented below. We will also tell you how to take the drug and why it is generally needed.
Composition, description and form
How is the Strattera sold? Customer reviews say that this tool can be found in pharmacies in the form of capsules of various colors, depending on the weight of the active ingredient.
The drugs referred to include such an active ingredient as atomoxetine hydrochloride. It also contains additional ingredients in the form of dimethicone, pregelatinized starch, titanium dioxide, gelatin, dyes and sodium lauryl sulfate.
Do you know what constitutes a stratter capsules? Reviews of doctors indicate that this drug belongs to the group of sympathomimetic drugs that have a central effect and have such a highly selective, powerful active ingredient as atomoxetine. The latter, by the way, is an inhibitor of norepinephrine (presynaptic) transporters.
The drug under consideration has a low affinity for other receptors of the noradrenergic system or neurotransmitter transporters.
The drug “Strattera”, reviews about which are mentioned, moreover, it is not a psychostimulant, nor does it refer to amphetamines. In the course of clinical trials, cancellation of treatment with this drug did not lead to negative symptoms or worsening of the disease symptoms.
How is the absorption of the drug “Strattera”? The reviews state that when taken orally, the active component of this tool is absorbed quickly and almost completely from the gastrointestinal tract. The highest concentration of atomoxetine in the blood is observed after 60-110 minutes.
The distribution of this drug in the human body is quite extensive. It binds well with plasma proteins, especially with albumin.
Atomoxetine (primary) is metabolised in the liver by the isoenzyme CYP2D6.
Following oral administration of capsules, the mean half-life of atomoxetine is 3.5 hours in extensive metabolisers and 21 hours in delayed patients.
The main way of removing this drug is through the renal system. Pharmacokinetics of the drug in children 6 years of age is similar to that in adults.
In what cases is the drug “stratter” most effectively manifested? Opinions of adults indicate that this drug is ideal for patients from the age of 6 years with attention deficit hyperactivity disorder.
Prohibitions on use
Are there any contraindications to taking Strattera medications? Testimonials (only an experienced doctor should prescribe this drug to children) state that the following conditions are an absolute ban on taking this drug:
- glaucoma is closed;
- severe heart damage;
- hypersensitivity to atomoxetine and other components of the drug;
- age up to 6 years;
- simultaneous treatment with MAO inhibitors.
Medicines for special purposes
The drug “Strattera”, reviews of which are more positive, is prescribed with caution when:
- joint treatment with psychostimulants;
- cardiovascular diseases;
- work associated with high physical loads;
- sudden cardiac death in history, seizures;
- circulatory disorders in the brain.
Capsules “Strattera” (drug): instructions
Experts’ opinions indicate that the tool under consideration is intended solely for oral administration, 1 time per day.
Treatment with this drug should only be carried out under the supervision of a doctor who specializes in treating people with ADHD.
Observing the negative effects in the case of a one-day use of capsules, it is recommended to divide the dose into 2 doses (preferably every 12 hours).
Canceling this tool almost never leads to negative symptoms, so treatment does not require a gradual reduction in doses.
The average recommended dose of this drug daily for children weighing up to 70 kg is 500 mcg / kg. Then this amount should be increased to the therapeutic amount of 1.2 mg / kg (not earlier than after 3 days).
In the absence of the desired therapeutic effect, it is possible to increase the dose to 1.8 mg / kg, but not earlier than 15-30 days after the start of treatment.
The average recommended dose for children weighing 70 kg and adults is 40 mg. Then the amount is increased to the therapeutic dose of 80 mg, but not earlier than in 3 days. In the absence of a therapeutic effect, the dose of the drug is increased to 120 mg (approximately 2-4 weeks later).
With moderate liver pathologies, the standard amount of the drug in question is reduced by half, and with severe symptoms – by four times.
What are the side effects of Strattera? Parent reviews
Parents of children from 6 years who used the drug for ADHD say, against the background of its administration, their children often suffered from abdominal pain and loss of appetite. Typically, these symptoms were transient and did not require treatment discontinuation.
Due to the decrease in appetite, some people showed a slight loss of body weight at the very beginning of treatment, which increased with increasing doses of the drug.
What are the other unwanted reactions of Stratter (medicine)? Patients report that this medicine causes nausea and vomiting, especially in the first month of treatment. In addition, some parents say that taking this drug increases the average heart rate by 6 beats per minute, and also increases diastolic and systolic blood pressure by 2 mm Hg. ul.
Side effects in adults
In adult patients receiving the study drug, the most commonly reported adverse reactions were related to the genitourinary system and gastrointestinal organs. These side effects include insomnia, loss of appetite, nausea, and dry mouth.
Also in adults there were:
- decreased libido, dizziness, weight loss, stomach pain, waking up early in the morning;
- redness (blood), sleep disturbance and sleep quality, difficulty urinating;
- tachycardia, constipation, sinus headache, excessive sweating, palpitations, drowsiness, weakness;
- urinary retention, chills, dysmenorrhea, indigestion, gas
- dermatitis, menstrual change, the absence or violation of ejaculation and erection, orgasm disorders, prostatitis;
- feeling cold in the legs, Raynaud’s syndrome, painful erection.
The active substance of the agent under consideration -Atomoxetine may cause irritation to the organs of vision. Therefore, when it comes into contact with the eye mucosa, rinse it with water immediately and report the incident to a doctor. Water should also be used to rinse all skin surfaces in contact with atomoxetine.
When should a patient be prescribed Strattera? References (only a qualified doctor should diagnose children with ADHD) say specialists that the detection of the presence of this disease is carried out in accordance with the criteria of ICD-10. The symptoms of this syndrome are manifested by a lack of concentration, frequent distraction, excessive impatience, impulsiveness, lack of organization, anxiety, and other similar disorders in human behavior.
According to pediatricians, suicidal thoughts may be observed in some children and adolescents against the background of “Stratters prima”. Therefore, during such therapy, the patient requires special monitoring.
If you have cramps that are not explained otherwise, stop taking Stratter capsules immediately. With extreme caution, this drug should be prescribed when seizures in history occur in humans.
It should also be noted that careful observation and a special approach to therapy is required in patients with symptoms of panic attacks, anxiety, agitation, impulsivity, insomnia, akathisia and irritability.
During treatment with this drug, people approaching adolescents and children are required to monitor the likely occurrence of all of the above symptoms and suicidal tendencies, in order to inform the pediatrician in time.
The safety and efficacy of Stratters preparations have not been studied in the elderly.
When using this medication by adults, care should be taken when performing delicate or dangerous work, and while driving.
Reviews of doctors and consumers
What do patients say about medicines like Strattera? Drug reviews leave a lot of people who have taken it on their own or have followed patients (including children).
According to experts, most often this tool is prescribed to children with an attention deficit. It should be noted that many parents do not want to give this drug to their children. This is often due to their personal concerns. After all, it’s no secret to anyone that any drugs have side effects. Despite this, some parents agreed to give their child a Stratter and their expectations did not disappoint. They argue that this drug has become an indispensable help in adjusting their children to normal life.
In addition to positive opinions about this, there are also negative messages. They talk about many side effects that are especially often observed at the very beginning of therapy. Doctors say that such reactions do not require treatment cancellation, however, some parents simply do not have enough restraint and patience to overcome this unique stage of their child’s adaptation to therapy. Although in some cases this drug is not suitable for single children.
From the foregoing, we can safely concludegenerally atomoxetine helps parents at some stage in their child’s life. Most of the people who underwent the full course of treatment were very satisfied with its effects. In addition, they claim that Strattera is currently the only effective drug for treating ADHD.
As for specialists, then take this or thatpage of the opinion of parents about the drug, and also to guarantee absolute safety or effectiveness for the child in question, they can not. Moreover, the diagnosis of ADHD can only be made by a highly competent physician who must in fact be determined by the treatment regimen.